what are two things Jekyll does to attempt to overcome Edward Hyde

He took more potion:

Accordingly, it became necessary for me to double, then triple, the dosage of the drug in order to keep Hyde in check.

He also stopped taking the potion:

Then, without warning one day, I was tortured with throbbing knots of lust and depravity. Hyde was struggling to be released. And in a moment of weakness, I gave him his freedom. I drank the potion and once more, Edward Hyde was freed.