In which ways does Ender alienated in both worlds

Ender feels alone on Earth because he is so unique. He doesn't have friends and is tormented by his brother. When Ender is chosen for the academy things get even worse for Ender. Ender is forced to pretty much be alone at the academy because the commanders are trying to observe and shape Ender under stress. When Ender nearly wipes out all the Buggers (they are actually nice aliens) he feels alienated once again.