by act 3 how has macbeths relationship with lady macbeth changed?

By this point in the play, Macbeth no longer confides in his wife or takes command from her. His plans are his own and L.Macbeth does not figure prominently in them. Macbeth has begun his one-way journey into the land of "crazy murderer". He has, more or less, shed his persona of the nervous indecisive man. When L.Macbeth asks what Macbeth plans are, he treats her like a helpless lady instead of his "boss", "be innocent of the knowledge dearest chuck."