Did Lady Macbeth experience any growth or changes during the story (explain)?

Lady Macbeth changes. As Macbeth heads closer to his undoing, the couple become estranged. The power shifts from L. Macbeth to Macbeth. L. Macbeth really doesn't figure into Macbeth's plans anymore. Consequently she becomes increasingly isolated and goes insane. By the end of the play, she seems plagued by guilt that she can't handle.