Pages 109 to 111 find vladek once again hiding from the Nazis. Can a mouse ever be a heroic character, or are they necesssarily passive creatures? Why or why not?

I think mice being heroic is what, at least in part, Speigelman had in mind. Mice are generally considered vermin, a sign of weak unsanitary animals. This is what Hitler thought of Jews. Many of the mice characters, like Vladek, turn out to be strong, intelligent, and resilient characters that learn how to survive the brutality of the Nazis.