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Throughout the story we see George struggle to hold onto a dream that includes Lennie. We see George's frustration as he lapses into his speech about what he could do without Lennie. Still George sticks by Lennie because he is all George has. Check out this GradeSaver description below,

George

George Milton. A migrant worker who travels from farm to farm with his mentally impaired friend Lennie during the Depression. The two dream of earning enough money to buy a small farm where Lennie can tend rabbits. By virtue of his mental superiority, George assumes a dominant role with Lennie, acting as a parent. Because Lennie tends to involve George in difficult predicaments, George must be responsible, level-headed and ready to deal with any tragedy that may arise. Despite the many problems that Lennie causes George, he stays with his simple-minded friend as a buffet against loneliness and he retains a palpable hope that the two will eventually leave the aimless life of a migrant worker to live a more fulfilling existence.