How does Curley's wife coming into Crooks' room emphasize the theme of loneliness?

Crooks is relishing the company he has with Lennie. It's not the most stimulating conversation but it is company he so terribly misses. Curley's wife comes by on the pretence of looking for Curley (she is always "looking" for Curley) Crooks tells her to leave. Curley's wife turns vicious and threatens to accuse Crooks of rape. For Crooks, the punishment would mean certain death. This is the only space he has. Crook's wants to keep a shred of dignity not be sworn at by Curley's wife. Curley's wife of course is aware of this but she does what any desperately lonely human might do to try to purge her frustrations. She visits someone off limits and then, when she can't have his company, threatens who she perceives is socially weaker than her,

An' what am I doin'? Standin' here talkin' to a bunch of bindle stiffs—a nigger an' a dum-dum and a lousy ol' sheep—an' likin' it because they ain't nobody else." (102)