What does Crooks say to Lennie about loneliness and how does this relate to this theme of the novel?

Crooks tells Lennie, "I tell ya a guy gets too lonely an' he gets sick.". The itinerant farm worker of the Great Depression found it nearly impossible to establish a fixed home. These men were forced to wander from ranch to ranch seeking temporary employment, to live in bunk houses with strangers, and to suffer the abuses of arbitrary bosses. George sums up the misery of this situation at several points during his monologues to Lennie - "Guys like us, that work on ranches, are the loneliest guys in the world. They got no family. They don't belong no place" (15). Crooks is worse of because he is isolated for being black.