Curley's wife is the one major female character in the novel, who is not even given a name of her own, does not fit neatly into either category. She is a domestic figure - after all, she is married to Curley and spends most of her time at home - and, at the same time, a flirtatious, highly sexualized figure. Her status, between domesticity and prostitution, makes her extremely problematic in the novel, a source of anxiety and unrest. She leads to trouble, as George immediately observes she will.
A reader might raise an eyebrow at Steinbeck's simple willingness to pin the role of trouble-maker on one unnamed woman. Curley's wife is regularly used as a scapegoat in the novel. She is blamed for the lustful feelings she inspires. Even after she has been tragically killed, Candy shouts misogynist insults at her corpse. Curley's wife's life, clearly, is miserable, yet we are not encouraged to see things from her perspective. Even when she expresses her miserable loneliness, these episodes are followed by instances of manipulation, of threatening. Her death is hardly poignant - and indeed, her corpse is praised more in death than she was in life. The reader has every reason to question Steinbeck's motives in giving us such an unsympathetic view of this woman - and, by association, women in general.
