One Flew Over the Cuckoo's Nest

How does Bromden know the EST is getting to mcmurphy, even though mcmurphy says and acts like they arent?

part 4, chapter 3

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Chief notices the changes in McMurphy because he's been visiting him regularly. He sees the exhaustion and dazed demeanor. He also sees McMurphy's reaction when his treatments are announced, as McMurphy's face tightens up, and the fear becomes visible in his eyes. 

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One Flew Over the Cuckoo's Nest