What were the physical and emotional effects of living in a Nazi occupied country as a Jew?

Just as the phrase "after the war" hangs unspoken over everyone in the annex, so does the phrase "the Jews outside." All of the annex residents struggle with feelings of guilt for those they have left behind to suffer under Nazi persecution. Some of them, like Mrs. Van Daan, choose to ignore it. Others, like Anne, feel bad but insist on trying to remain cheerful. The question of how the annex residents deal with their feelings about the suffering outside is intimately linked to their own feelings of fear about being captured by the Germans.

Physical effects depended upon the conditions.... hunger and illness.