What is the historical significance of the name given to the place where the parties take place? How does it relate to the women who live/work there?

The hotel that they parties take place is called Jezebel's. Jezebel was a Phoenician princess and queen of Israel as the wife of Ahab. According to the Bible, she encouraged idolatry and was ultimately killed by Jehu. The women that work there are considered impure or unrighteous like Jezebel was.