Do melodies touch human heart?What was the effect of 'Two Lovely Black eyes'on Harris and the writer?

The men, miserable, pass the time by playing penny nap, a card game, and listening to George play the banjo. Although J. describes him as an unskilled player elsewhere in the book, George here plays a mournful rendition of “Two Lovely Black Eyes” that plunges the men further into depression. Yes, music seems to touch people in all cultures.