Twelve Angry Men is an American courtroom drama written by Reginald Rose. It may also refer to:
- "Twelve Angry Men" (Studio One), a 1954 teleplay by Reginald Rose for the American anthology television series Studio One
- Twelve Angry Men (1955 play), adapted by Sherman L. Sergel from the teleplay
- Twelve Angry Men (1964 play), Reginald Rose's own stage version
- 12 Angry Men (1957 film), adapted from the 1954 teleplay
- 12 Angry Men (1997 film), a made-for-television remake of the 1957 film
- "Twelve Angry Men" (Hancock's Half Hour), a 1959 episode of the British comedy television series Hancock's Half Hour
- "12 and a Half Angry Men", an episode of the animated TV series Family Guy