This is a smart, lucid, and thorough lecture from Ian Johnston, a professor at Malaspina University-College in Canada.
http://www.mala.bc.ca/~johnstoi/introser/marquez.htm
Although he occasionally gets wrapped up in theoretical aspects (fortunately most theoretical terms have definitions in the text), his comments on looking at Solitude as an epic and the concept of time in the novel are particularly good. This is a helpful link if your own professor didn't give the best lecture on the book.
This link is practically a mini-ClassicNote in itself.
http://www.hotchkiss.k12.co.us/HHS/nobelnov/marquez.htm
As part of a class at Hotchkiss Academy, the instructor put together a list of essay questions and extensive commentary on the style, structure, and techniques of Solitude. If you're just interested in essay topics, they're at the very top of the page. The rest of the page goes in-depth and includes a plot summary. There's also a very cute picture of Gabriel Garcia Marquez at the top.
This is a New York Times book review of One Hundred Years of Solitude from 1970,
http://www.nytimes.com/books/97/06/15/reviews/marque-solitude.html
when it first appeared in English, written by the beloved Harvard professor Robert Kiely. This link is excellent because it is a view into people's reaction to the book 30 years ago, before critical analysis made it a classic. A great idea if you're doing a paper on the impact of the book when it first came out.
A look at Marquez and the book from a Latin American perspective
http://polyglot.lss.wisc.edu/laisp/cl/clcompweb.html
courtesy of the Latin American Studies department at the University of Wisconsin. The site includes two biographies (one in English, the other in Spanish) and one of Marquez's short stories in the original Spanish. For an enormous, wonderful list of biographies, news articles, bibliographies and reviews, click on the link "General Site."