Principles of Anatomy and Physiology 14e with Atlas of the Skeleton Set (14th Edition)

Published by Wiley
ISBN 10: 1-11877-456-6
ISBN 13: 978-1-11877-456-4

Chapter 12 - Nervous Tissue - Figure 12.15 - Page 417: 2

Answer

Ligand-gated ion channels are located in the following sites: the dendrites of sensory neurons; the dendrites and cell bodies of interneurons and motor neurons. Examples of ligand neurotransmitters are acetylcholine (ACH), norepinephrine, and glycine.

Work Step by Step

When ACH binds to membrane receptors, it opens up cation channels that allow Na+ ions, and Ca++ ions into the cell, but permits the outflow of K+ ions. The influx of Na+ ions is greater than the efflux of K+ ions , so the result is a depolarizing graded potential. On the other hand the binding of the neurotransmitter glycine to membrane receptors opens up ion channels that let CL- anions into he cell. The result is a hyperpolarization of the neuron.
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