Answer
The proton gradient established by the electron transport chain (ETC) is the driving force behind ATP production in oxidative phosphorylation.
In brown adipose tissue, the free flow of protons into the inner mitochondrial membrane through uncoupling proteins distorts the proton gradient and disrupts the relationship between the ETC and oxidative phosphorylation, which in turn will reduce ATP synthesis.
Work Step by Step
Brown adipose tissue maintains body temperature in neonates, and its main role is the generation of heat. This is facilitated by the movement of protons across the gradient through the uncoupling proteins. Hence, these cells have less proton motive force and less ATP production.
