Essential Cell Biology, 4th Edition

Published by Garland Science
ISBN 10: 0815344546
ISBN 13: 978-0-81534-454-4

Chapter 11 - Membrane Structure - Questions - Page 368: Question 11-3

Answer

See explanation

Work Step by Step

Fluidity refers to movement within a single leaflet, which is rapid. Asymmetry refers to differences between the two leaflets, which are maintained over time because flip-flop between leaflets is energetically unfavorable and requires enzymes. So the membrane can be fluid in-plane (lipids moving side-to-side) while still being asymmetric across leaflets. Because fluidity of the bilayer is based on one plane, lipid molecules diffuse laterally in a monolayer but do not flip between these specific monolayers. Thus, specific lipid molecules inserted into one monolayer remain in it unless they are actively transferred by a flippase enzyme
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