Essential Cell Biology, 4th Edition

Published by Garland Science
ISBN 10: 0815344546
ISBN 13: 978-0-81534-454-4

Chapter 12 - Transport Across Cell Membranes - Questions - Page 395: Question 12-2

Answer

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Work Step by Step

The plasma membrane Na+ pump in cardiac muscle cells is only partially inhibited by oubabin and digitalis, which lowers the quantity of Ca2+ being pumped out of the cell. Muscle contractions become stronger as a result of an increase in intracellular Ca2+ concentration. The removal of extracellular Ca2+ by the antiport, which swaps Ca2+ for extracellular Na+ across the plasma membrane, is essential for allowing the muscle cells to relax. The concentration of intracellular Ca2+ rises when the Na+ pump is partially inhibited by Ouabain or digitalis, resulting in a stronger contraction of the heart muscle cells.
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