Fundamentals of Biochemistry: Life at the Molecular Level 5th Edition

Published by Wiley
ISBN 10: 1118918401
ISBN 13: 978-1-11891-840-1

Chapter 15 - Glucose Catabolism - Exercises - Page 521: 28

Answer

Normally PFK-1 is activated by AMP and phosphate (and inhibited by ATP) so i would imagine PFK-1 would be more active in the brain and less active in the liver because of the particular concentrations. This makes sense to me because the brain depends on glucose breakdown much more than the liver does.

Work Step by Step

Normally PFK-1 is activated by AMP and phosphate (and inhibited by ATP) so i would imagine PFK-1 would be more active in the brain and less active in the liver because of the particular concentrations. This makes sense to me because the brain depends on glucose breakdown much more than the liver does.
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