Fundamentals of Biochemistry: Life at the Molecular Level 5th Edition

Published by Wiley
ISBN 10: 1118918401
ISBN 13: 978-1-11891-840-1

Chapter 20 - Lipid Metabolism - Exercises - Page 715: 1

Answer

Glycerol Kinase and Glycerol-3-Phosphate dehydrogenase on glycerol produces Dihydroxyacetone phosphate(DHAP). DHAP is converted to Glyceraldehyde-3-Phosphate which is an intermediate of glycolytic pathway

Work Step by Step

When Glycerol Kinase acts on Glycerol, Glycerol-3-Phosphate is produced. Further, FADH dependent Glycerol-3-Phosphate dehydrogenase(G3PDH)(enzyme present in membrane) acts on Glycerol-3-Phosphate to give Dihydroxyacetone phosphate (DHAP). DHAP formed is then converted to glyceraldehyde-3-Phosphate which enters the glycolytic pathway Note: Cytosolic Glycerol-3-Phosphate dehydrogenase is NADH dependent and it acts on Glycerol-3-Phosphate to give DHAP
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