Fundamentals of Biochemistry: Life at the Molecular Level 5th Edition

Published by Wiley
ISBN 10: 1118918401
ISBN 13: 978-1-11891-840-1

Chapter 9 - Lipids and Biological Membranes - Exercises - Page 291: 32

Answer

Phospholipase A 2 is an enzyme that cleaves the glycerol bond to the fatty acid tail. The cell membranes major component is the phospholipid. It maintains the structural integrity of a membrane and provides to its intactness. Phospholipase destroys the integrity and causes the cell to rupture. Exogenous supply of phospholipase A2 from snake venom is very damaging and destroys the cell membrane of a healthy cell functioning to fulfil the body's metabolic needs. Whereas endogenous phospholipase A2 is beneficial as if a cell injury occurs it further breaks the cell and stops a bad cell to perform incorrect functions. Endogenous phospholipase helps to form endocytic vesicles which fuse to the outer of the cell membrane as it digests the membrane and helps the transport of important material within the vesicle to outer cell cytoplasm.

Work Step by Step

Phospholipase A 2 is an enzyme that cleaves the glycerol bond to the fatty acid tail. The cell membranes major component is the phospholipid. It maintains the structural integrity of a membrane and provides to its intactness. Phospholipase destroys the integrity and causes the cell to rupture. Exogenous supply of phospholipase A2 from snake venom is very damaging and destroys the cell membrane of a healthy cell functioning to fulfil the body's metabolic needs. Whereas endogenous phospholipase A2 is beneficial as if a cell injury occurs it further breaks the cell and stops a bad cell to perform incorrect functions. Endogenous phospholipase helps to form endocytic vesicles which fuse to the outer of the cell membrane as it digests the membrane and helps the transport of important material within the vesicle to outer cell cytoplasm.
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