Lehninger Principles of Biochemistry 6th Edition

Published by W.H. Freeman
ISBN 10: 1-42923-414-8
ISBN 13: 978-1-42923-414-6

Chapter 12 - Biosignaling - Problems - Page 498: 9

Answer

$Amplification$ results as one molecule of a catalyst activates many molecules of another catalyst. An amplification cascade involving, in order; Insuline receptor (IRS-1), Raf, MEK, ERK, ERK activates a transcription factor, which stimulates mRNA production.

Work Step by Step

These are all the sources of amplification in the insulin receptor system.
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