Answer
Integral membrane proteins are called intrinsic proteins. They have segments embedded in the phospholipid bilayer and usually have residues with hydrophobic side chains. These residues interact with fatty acyl group.
Peripheral membrane proteins are called extrinsic proteins that do not interact with hydrophobic core of phospholipid bilayer. They are bound to the membrane by indirect interaction with integral membrane protein or direct interaction with lipid polar head groups.
Work Step by Step
Integral membrane proteins are called intrinsic proteins. They have segments embedded in the phospholipid bilayer and usually have residues with hydrophobic side chains. These residues interact with fatty acyl group.
Peripheral membrane proteins are called extrinsic proteins that do not interact with hydrophobic core of phospholipid bilayer. They are bound to the membrane by indirect interaction with integral membrane protein or direct interaction with lipid polar head groups.