Answer
Nucleotide-binding oligomerization domain (NOD) proteins and Toll-like receptors (TLRs) are two classes of PRRs. Both play a role in innate immune detection. They differ because NOD molecules reside within the cytoplasm of a host cell cell, where they detect microbes that try to gain entry into host cells. Comparatively, Toll-like receptors are merely a family of membrane-bound receptors. TLRs bind to microbial molecules.
Work Step by Step
Nucleotide-binding oligomerization domain (NOD) proteins and Toll-like receptors (TLRs) are two classes of PRRs. Both play a role in innate immune detection. They differ because NOD molecules reside within the cytoplasm of a host cell cell, where they detect microbes that try to gain entry into host cells. Comparatively, Toll-like receptors are merely a family of membrane-bound receptors. TLRs bind to microbial molecules.
