Answer
C
Work Step by Step
The major inflammatory mediator released by degranulating mast cells in type I hypersensitivity is histamine. Histamines are integrally involved in inflammatory responses and they are the primary cause of itching.
You can help us out by revising, improving and updating this answer.
Update this answerAfter you claim an answer you’ll have 24 hours to send in a draft. An editor will review the submission and either publish your submission or provide feedback.