Answer
The substituents don't fit into the receptor due to the fact that the enzyme works by a lock-and-key mechanism. The enantiomers cannot be superimposed and thus the mechanism cannot work.
Chemistry: An Introduction to General, Organic, and Biological Chemistry (12th Edition)
by Timberlake, Karen C.
Published by
Prentice Hall
ISBN 10:
0321908449
ISBN 13:
978-0-32190-844-5
Chapter 13 - Section 13.2 - Chiral Molecules - Figure 13.7 - Page 443: 1
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