Organic Chemistry (8th Edition)

by Wade Jr., L. G.

Published by Pearson

ISBN 10: 0321768418

ISBN 13: 978-0-32176-841-4

Chapter 24 - Amino Acids, Peptides, and Proteins - Problems - Page 1163: Problem 24-4 a

Answer

The structure of the predominant form of isoleucine at pH 11 is shown in the picture below.

Work Step by Step

The general rule when determining if a group will be protonated is: at solution pH below the group's pKa value, the group will be protonated; at pH higher than the group's pKa value, it will not be protonated.

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