Answer
Partial cleavage of peptides can be accomplished either by using dilute acid with a shortened reaction time or by using enzymes, such as trypsin and chymotrypsin, that break bonds between specific amino acids.
Cleavage by trypsin and chymotrypsin is shown in the picture below.
Work Step by Step
Trypsin cleaves the chain at the carboxyl groups of the basic amino acids lysine and arginine.
Chymotrypsin cleaves the chain at the carboxyl groups of the aromatic amino acids phenylalanine, tyrosine, and tryptophan.
