Answer
$16$
Work Step by Step
RECALL:
(1) $a^{-m} = \dfrac{1}{a^m}$
(2) $\dfrac{a^m}{a^n} = a^{m-n}$
(3) $\left(\dfrac{a}{b}\right)^m=\dfrac{a^m}{b^m}$
(4) $(ab)^m = a^mb^m$
Use rule (2) above to obtain:
$\dfrac{4^8}{4^6}=4^{8-6} = 4^2 = 16$