Principles of Anatomy and Physiology 14e with Atlas of the Skeleton Set (14th Edition)

Published by Wiley
ISBN 10: 1-11877-456-6
ISBN 13: 978-1-11877-456-4

Chapter 19 - The Cardiovascular System: The Blood - Critical Thinking Questions - Page 687: 1

Answer

Some bacteria are pathological and cause several infectious diseases. But some are part of our essential microbiome and live in our GI tract and other parts of our body. We can't maintain perfect health without them. The first kind caused Mr. Shipla's bladder infection, and they were promptly dispatched by treatment with an antibiotic. In this case the antibiotic was a broad spectrum antibiotic ; this means it was not carefully chosen to deal with the pathogen that caused the bladder infection; it killed not only the microbes that caused the bladder infection, but in addition killed several other species or strains of bacteria , some of which were beneficial, This is like firing a blunderbuss at a mosquito. In this case many of the bacteria killed are those that are necessary in our bodies to enable us to synthesize Vitamin K. Since Vitamin K is essential for the making of clotting factors II, VII IX, and X, this treatment would cause Mr. Shipla to experience clotting problems-- temporarily-- that could lead to abnormal bleeding. This condition would be cured as the vitamin-K-synthesizing bacteria repopulated the intestines, and normal levels of Vitamin K were once again produced.

Work Step by Step

The return of normal levels of Vitamin K would cause production of normal amounts of clotting factors (II, VII, IX and X) and the disappearance of Mr Shipla.s bleeding susceptibilities.
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