Principles of Anatomy and Physiology 14e with Atlas of the Skeleton Set (14th Edition)

Published by Wiley
ISBN 10: 1-11877-456-6
ISBN 13: 978-1-11877-456-4

Chapter 29 - Development and Inheritance - Checkpoint - Page 1123: 37

Answer

Genomic imprinting is a phenomenon in which the expression of a gene (genes) depends on whether the gene(s) came from father; in other words, this ia a " parent-of -origin- gene- expression." Examples of human conditions in which genomic printing operates are Praeder Willi syndrome, Angelmann syndrome, Beckwith Wiedeman syndrome and Albright hereditary osteodystrophy. In Prader Willi and Angelman syndromes autosome #15 is involved. In both these conditions a part of chromosome # 15 is deleted. If the defective chromosome is inherited from the father, the syndrome that results is called Praeder Willi syndrome. However, if the defective #15 is transmitted by the mother, the syndrome that results is called Angelmann syndrome.

Work Step by Step

Some symptoms and signs (SS) of Praeder Willi are learning disability, short stature, hypogonadism and obesity. Some ways in which Angelmann's syndrome may be expressed are learning difficulties, speech problems, ataxia, depression, and hyperactivity.
Update this answer!

You can help us out by revising, improving and updating this answer.

Update this answer

After you claim an answer you’ll have 24 hours to send in a draft. An editor will review the submission and either publish your submission or provide feedback.