Biological Science (6th Edition)

Published by Benjamin Cummings
ISBN 10: 0321976495
ISBN 13: 978-0-32197-649-9

Chapter 3 - Protein Structure and Function - Review - Case Study - Page 92: 16

Answer

The AN-PEP enzyme can serve as a potential therapeutic drug in patients suffering from the celiac disorder as it digests proline-rich peptides that can trigger an immune response.

Work Step by Step

People affected by the celiac disorder have an overactive immune response to proline residues that results from partial gluten digestion by normal gut enzymes. When these people are treated with AN-PEP, its ability to digest those residues is a good indicator that it can potentially be used as a therapeutic drug for the disease.
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