Biological Science (6th Edition)

Published by Benjamin Cummings
ISBN 10: 0321976495
ISBN 13: 978-0-32197-649-9

Chapter 8 - Energy and Enzymes: An Introduction to Metabolism - Review - Case Study - Page 188: 15

Answer

It is given that PAH can form one active site based on the amino acid sequence and that the functional form of the enzyme has four identical active sites. It is evident that PAH is made up of four identical protein subunits, with each subunit containing the same active site.

Work Step by Step

The primary sequence determines the active site. If one active site can be formed from a particular sequence, protein folding will always yield only one active site. Some enzymes are made up of many subunits. Sometimes these subunits may be identical (as in PAH), and sometimes they may differ (as in insulin).
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