Fundamentals of Biochemistry: Life at the Molecular Level 5th Edition

Published by Wiley
ISBN 10: 1118918401
ISBN 13: 978-1-11891-840-1

Chapter 23 - Nucleotide Metabolism - Exercises - Page 829: 31

Answer

gout is more prevalent in populations that eat relatively large amounts of meat due to the high purine content of meat, which can lead to an increase in uric acid levels in the body.

Work Step by Step

Meat is a rich source of purines, particularly red meat and organ meats such as liver, kidney, and sweetbreads. When purines are broken down by the body, uric acid is produced as a waste product. Therefore, consumption of meat can lead to an increase in uric acid levels in the body, particularly in individuals with impaired uric acid excretion or overproduction. uric acid can lead to the formation of crystals in the joints, causing gout.
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