Fundamentals of Biochemistry: Life at the Molecular Level 5th Edition

Published by Wiley
ISBN 10: 1118918401
ISBN 13: 978-1-11891-840-1

Chapter 4 - Amino Acids - Exercises - Page 95: 23

Answer

a) pI = (2.35 + 9.87) / 2 = 6.11 b) pI = (6.04 + 9.33) / 2 = 7.68 c) pI = (2.10 + 4.07) / 2 = 3.08

Work Step by Step

pI is the isoelectric point. In other words, it is the pH at which the amino acid is neutral pI Formula: (pKa1 + pKa2) / 2 Example: Asp is neutral between pH 1.88 and 3.65. So, pI = (1.88 + 3.65) / 2 = 2.76
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