Answer
F-actin is a vital protein that can regulate cellular motility and function. This filamentous protein is required for normal immunological functions locomotion, endocytosis, signal transduction, etc. The deficiency of these F-actin binding proteins may lead to autoimmunity or autoinflammatory diseases. Basically, these binding proteins act as a regulator of tolerance and immune responses. The binding protein, Filamin binds to actin filaments to help in the phagocytosis of macrophages. It has also been suggested that filamin can ingest macrophages.
Work Step by Step
F-actin is a vital protein that can regulate cellular motility and function. This filamentous protein is required for normal immunological functions locomotion, endocytosis, signal transduction, etc. The deficiency of these F-actin binding proteins may lead to autoimmunity or autoinflammatory diseases. Basically, these binding proteins act as a regulator of tolerance and immune responses. The binding protein, Filamin binds to actin filaments to help in the phagocytosis of macrophages. It has also been suggested that filamin can ingest macrophages.
