Cronos
After the alchemist's death all of the contents of his home were seized and sold. Ironically, the cronos was not on the inventory list of items seized/sold.
A Toy
Jesús sees the cronos as a funny toy as he begins to work with it. Ironically it pierces him deeply with metal stinger that cut his hand badly.
Blood
Jesús is about to drink the blood of a man who had a bloody nose in the bathroom. Ironically, a man comes from the stall and washes it all down the drain before he can do so.
Cremation
The mortician is stitching up Jesús for his burial. Ironically, the funeral director tells the man that he doesn't need to do it because he is being cremated.
Way Out
Jesús asks De la Guardia for a way out of what is happening to him in exchange for the cronos. Ironically, the way out De la Guardia has is killing Jesús.