Answer
$252$
Work Step by Step
The product of two numbers with opposite signs is negative while the product of two numbers with the same sign is positive. Multiplying the numbers from left-to-right, then the given expression, $
3\cdot(-7)\cdot(-2)\cdot6
$, simplifies to
\begin{array}{l}
-21\cdot(-2)\cdot6
\\\\=
42\cdot6
\\\\=
252
.\end{array}