Principles of Anatomy and Physiology 14e with Atlas of the Skeleton Set (14th Edition)

Published by Wiley
ISBN 10: 1-11877-456-6
ISBN 13: 978-1-11877-456-4

Chapter 3 - The Cellular Level of Organization - Checkpoint - Page 98: 28

Answer

Interphase is significant because it is during interphase that the cell prepares for successful duplication --mitosis or meiosis. For a given cell cycle the cell spends most of its time in interphase acrrying out the following processes, growth, DNA replication and protein synthesis.

Work Step by Step

Interphase comprises three (or four) stages: G0, G1, S, G2. In G1 phase, there is great metabolic activity in the cell: organelles are replicated, centrosome duplication begins, and some cytosolic substances are synthesized. No DNA replication takes place in this stage. Some cells like nerve cells, remain a long time, or indefinitely in a modified G1 state referred to as a GO stage. However, most cells move on into the synthesis or S phase that commits them to go through to mitosis or meiosis. The S phase ( or stage) is the phase of DNA replication. The uncoiling of the double stranded DNA and the assembling of complimentary strands takes time, so this is normally longest stage in interphase. Centrosome and centriole replication begin. In G2 cell growth continues , cenrtosome replication is completed and some enzymes and other proteins are synthesized
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