Fundamentals of Biochemistry: Life at the Molecular Level 5th Edition

Published by Wiley
ISBN 10: 1118918401
ISBN 13: 978-1-11891-840-1

Chapter 13 - Biochemical Signaling - Exercises - Page 440: 9

Answer

The SH2 domain in a tyrosine phosphatase of STAT factor helps in recognition and binding of it to the phosphorylated tyrosine residue on the receptor and they after dephosphorylating it can initiate the expression of required gene in JAK-STAT pathway.

Work Step by Step

The SH2 domain in a tyrosine phosphatase of STAT factor helps in recognition and binding of it to the phosphorylated tyrosine residue on the receptor and they after dephosphorylating it can initiate the expression of required gene in JAK-STAT pathway.
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