Answer
The SH2 domain in a tyrosine phosphatase of STAT factor helps in recognition and binding of it to the phosphorylated tyrosine residue on the receptor and they after dephosphorylating it can initiate the expression of required gene in JAK-STAT pathway.
Work Step by Step
The SH2 domain in a tyrosine phosphatase of STAT factor helps in recognition and binding of it to the phosphorylated tyrosine residue on the receptor and they after dephosphorylating it can initiate the expression of required gene in JAK-STAT pathway.