Answer
DNP and related compounds dissipate the proton gradient required for ATP synthesis. The dissipation of the gradient decreases the rate of synthesis of ATP, decreasing the ATP mass action ratio. Decreasing this ratio relieves the inhibition of the electron transport chain, causing an increase in metabolic rate.
Work Step by Step
DNP and related compounds dissipate the proton gradient required for ATP synthesis. The dissipation of the gradient decreases the rate of synthesis of ATP, decreasing the ATP mass action ratio. Decreasing this ratio relieves the inhibition of the electron transport chain, causing an increase in metabolic rate.
