Answer
About 2.5 ATP per NADH are produced when NADH participates
in the malate–aspartate shuttle.
Work Step by Step
The aspartate is transported out of the mitochondria where it is converted back to oxaloacetate and glutamate. The cycle is completed when glutamate goes back into the mitochondria. In this shuttle, 2.5 ATP molecules are produced for each cytosolic NADH because it is effectively transferred into the matrix as NADH.
