Fundamentals of Biochemistry: Life at the Molecular Level 5th Edition

Published by Wiley
ISBN 10: 1118918401
ISBN 13: 978-1-11891-840-1

Chapter 13 - Biochemical Signaling - Exercises - Page 441: 30

Answer

Pertussis toxin inhibits the activitation of phospholipase C. The mechanism involves ADP-ribosylation of the G protein coupled to the formyl peptide receptor that activates phospholipase C.With ADP ribosylation, the activity of phospholipase C is hindered.

Work Step by Step

Pertussis toxin inhibits the activitation of phospholipase C. The mechanism involves ADP-ribosylation of the G protein coupled to the formyl peptide receptor that activates phospholipase C.With ADP ribosylation, the activity of phospholipase C is hindered.
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