Fundamentals of Biochemistry: Life at the Molecular Level 5th Edition

Published by Wiley
ISBN 10: 1118918401
ISBN 13: 978-1-11891-840-1

Chapter 22 - Mammalian Fuel Metabolism: Integration and Regulation - Exercises - Page 800: 13

Answer

insulin would be expected to increase the activity of ATP-citrate lyase.

Work Step by Step

By boosting the activity of ATP-citrate lyase, which in turn raises the formation of acetyl-CoA, a precursor for fatty acid synthesis, insulin boosts the synthesis of fatty acids. As a result, insulin encourages the storage of extra glucose as fat by boosting ATP-citrate lyase activity.
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