Answer
$ \frac{256n^8}{t^4p^8}$.
Work Step by Step
The rule $(\frac{a}{b})^n = \frac{a^n}{b^n}$.
$(\frac{-4n^2}{tp^2})^4 = \frac{(-4)^4n^{2\times4}}{t^4p^{2\times4}} = \frac{256n^8}{t^4p^8}$.
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