Fundamentals of Biochemistry: Life at the Molecular Level 5th Edition

Published by Wiley
ISBN 10: 1118918401
ISBN 13: 978-1-11891-840-1

Chapter 17 - Citric Acid Cycle - Exercises - Page 586: 1

Answer

14CO2 will be released in the second round of the cycle. Acetyl from acetyl CoA acts as the C4 carbon of succinyl CoA. Succinyl CoA is cconverted to succinate, which is converted to fumarate, which is converted to malate, which is converted to oxaloacetate. Oxaloacetate will have 14C either at C1 or C4. Both of these carbons will be converted to carbon dioxide during the second round of the cycle.

Work Step by Step

14CO2 will be released in the second round of the cycle. Acetyl from acetyl CoA acts as the C4 carbon of succinyl CoA. Succinyl CoA is cconverted to succinate, which is converted to fumarate, which is converted to malate, which is converted to oxaloacetate. Oxaloacetate will have 14C either at C1 or C4. Both of these carbons will be converted to carbon dioxide during the second round of the cycle.
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