Fundamentals of Biochemistry: Life at the Molecular Level 5th Edition

Published by Wiley
ISBN 10: 1118918401
ISBN 13: 978-1-11891-840-1

Chapter 17 - Citric Acid Cycle - Exercises - Page 586: 6

Answer

Pyruvate dehydrogenase phosphate reverse the effects of pyruvate dehydrogenase kinase upon pyruvate dehydrogenase. It helps in linking the glycolysis metabolic pathway to the citric acid cycle and releasing energy via NADH. During exercise, when there is increased demand of energy, glycolysis pathway is disturbed in the absence of PDP, so exercise is not tolerated.

Work Step by Step

Pyruvate dehydrogenase phosphate reverse the effects of pyruvate dehydrogenase kinase upon pyruvate dehydrogenase. It helps in linking the glycolysis metabolic pathway to the citric acid cycle and releasing energy via NADH. During exercise, when there is increased demand of energy, glycolysis pathway is disturbed in the absence of PDP, so exercise is not tolerated.
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