Fundamentals of Biochemistry: Life at the Molecular Level 5th Edition

Published by Wiley
ISBN 10: 1118918401
ISBN 13: 978-1-11891-840-1

Chapter 14 - Introduction to Metabolism - Exercises - Page 476: 10

Answer

NAD+/NADH are the reduced form of NAD whereas the NADP+/NADPH are the reduced equivalents of NADP. The net charge of both these cofactors is different. NAD+ can accept two electrons and one proton to become reduced to NADH. This reduced form can be further used to donate electrons. Thus, the net charge of NAD+/NADH is -1/-2 whereas that of the other cofactor NADP+/NADPH is -3/-4.

Work Step by Step

NAD+/NADH are the reduced form of NAD whereas the NADP+/NADPH are the reduced equivalents of NADP. The net charge of both these cofactors is different. NAD+ can accept two electrons and one proton to become reduced to NADH. This reduced form can be further used to donate electrons. Thus, the net charge of NAD+/NADH is -1/-2 whereas that of the other cofactor NADP+/NADPH is -3/-4.
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