Answer
a. Compound Q, a metabolic inhibitor of enzyme B, causes Z to build up. Z must be the substrate for B
b. A mutant in enzyme C requires Y for growth. The mutant cannot make Y therefore Y must be the product of C.
c. An inhibitor of enzyme A causes W, Y and Z to accumulate. The enzyme A inhibitor causes intermediates before it in the pathway to build up.
d. Compound P, a metabolic inhibitor of enzyme C, causes W and Z to build up. As above, W and Z come before enzyme C.
Work Step by Step
a. Compound Q, a metabolic inhibitor of enzyme B, causes Z to build up. Z must be the substrate for B
b. A mutant in enzyme C requires Y for growth. The mutant cannot make Y therefore Y must be the product of C.
c. An inhibitor of enzyme A causes W, Y and Z to accumulate. The enzyme A inhibitor causes intermediates before it in the pathway to build up.
d. Compound P, a metabolic inhibitor of enzyme C, causes W and Z to build up. As above, W and Z come before enzyme C.